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The main green tea polyphenolepigallocatechin-3-gallate counteractssemen-mediated enhancement of HIV infection I
Ilona Hauber, Heinrich Hohenberg, Barbara Holstermann, Werner Hunstein, and Joachim Hauber PNAS Early Edition、2009

Patterns of MMP-2 and MMP-9 expression in human cancer cell lines
Roomi MW, Monterrey JC, Kalinovsky T, Rath M, Niedzwiecki A
Oncology Reports, 2009, 21, 1323-1333

Suppression of Human Rheumatoid Synovial Fibroblast MMP-2 Expression and Marix Invasion by Nutrient Synergy
M.W. Roomi, V. Ivanov, A. Niedzwiecki, M. Rath
Matthias Rath Research, Cancer Research Division, Santa Clara, CA 95050

Presented at: 9th World Congress of the Osteoarthritis Research Society International, Chicago, Illinois, December 2-5, 2004.
Published in: Osteoarthritis and Cartilage

Nutrient Mixture Prevents Hyper-Reactive Response Of Bronchial Muscle To Inflammatory And Allergic Stimuli.
Ivanov V, Roomi MW, Niedzwiecki A, Rath M
Matthias Rath Research Institute BV, Santa Clara, CA.

Presented at: 46th Annual Meeting of the American College of Nutrition, Charleston, South Carolina, Sept 22-25, 2005.
Published in: Journal of the American College of Nutrition, vol 24(5), Oct 2005
Effects of a nutrient mixture on infectious properties of the highly pathogenic strain of avian influenza virus A/H5N1

Deryabin PG, Lvov DK, Botikov AG, Ivanov V, Kalinovsky T, Niedzwiecki A, Rath M
Biofactors, 2008, 33, 85-97
Suppression of influenza A virus nuclear antigen production and neuraminidase activity by a nutrient mixture containing ascorbic acid, green tea extract and amino acids.
Jariwalla R, Roomi MW, Gangapurkar B, Kalinovsky T, Niedzwiecki A, Rath M
Biofactors, 2007, 31 (1),1-15.

Modulation of N-Methyl –N-Nitrosourea-Induced Mammary Tumors in Sprague-Dawley Rats by Combination of Lysine, Proline, Arginine, Ascorbic Acid and Green Tea Extract
M.W. Roomi, V. Ivanov ,T. Kalinovsky, A. Niedzwiecki, M. Rath
Breast Cancer Research, 2005, 7:R291-R295.

Inhibition of Matrix Metalloprotenase-2 Secretion and Invasion by Human Ovarian Cancer Line SK-OV-3 with Lysine,Proline, Arginine, Ascorbic Acid and Green Tea Extract
Roomi MW, Ivanov V, Kalinovsky T, Niedzwiecki A,
Rath M
Journal of Obstetrics and Gynecology, 2006, 32 (2), 148-154.

A natural Anti-Cancer formula-A specific formulation of nutrients containing lysine, praline, ascorbic acid, and epigallocatechin gallate inhibits matrix metalloproteinases activity and invasion potential of human cancer cell lines.
Roomi MW , Netke SP, Ivanov V, , Rath M. Niedzwiecki A
European Cancer Journal, 38, Suppl.7/Abs.280,2002

“Botanical Medicine in Clinical Practice”
Chapter 23, “Micronutrients and Nutrient Synergy in Immunodeficiency and Infectious Disease”
Jariwalla R, Niedzwiecki A, Rath M
Watson, R. R. and Preedy, V. R. (eds) (2008), CABI, Wallingford, UK

Inhibitory Effects of Ascorbic Acid, Proline, and Lysine Supplementation on Matrigel Invasion by Human Breast Cancer Cells MDA-MB-231 (2002)
Netke SP, Ivanov V, Roomi MW, Niedzwiecki A, Rath M.

Nutrient Synergy – A Specific Formulation of Nutrients Containing Lysine, Proline, Ascorbic Acid, and Epigallocatechin Gallate Inhibits Matrix Metalloproteinases Activity and Invasion Potential of Human Cancer Cell Lines (2002)
Room MW, Netke SP, Ivanov V, Niedzwiecki A, Rath M.

Anticancer Effect of Lysine, Proline, Arginine, Ascorbic Acid and Green Tea Extract on Human Renal Adenocarcinoma Line 786-0 (2004)
M.W. Roomi, V. Ivanov, A. Niedzwiecki, M. Rath
The Third International Kidney Cancer Symposium proceedings, Abstract #39, pg 39.

In vitro Expression of MMP-2 and MMP-9 by Human Renal Cell Carcinoma with Modulation by Phorbol Ester, TNF-alpha, Il-1 beta and Lipopolysaccharides (2004)
M.W. Roomi, V. Ivanov, A. Niedzwiecki, M. Rath
Third International Kidney Cancer Symposium proceedings, Abstract #40, pg 40.

A Specific Combination of Ascorbic Acid, Lysine, Proline and Epigallocatechin Gallate Inhibits Proliferation and Extracellular Matrix Invasion of Various Human Cancer Cell Lines (2003)
Netke SP, Roomi MW, Roomi NW, Ivanov V, Niedzwiecki A, Rath M.
Research Communications in Pharmacology and Toxicology: Emerging Drugs, 2:37-5, 2003.

Nutrient Synergy – an Important Inhibitor of MMP-2 Expression and Invasion by Human Ovarian Cancer Cell Line SK-OV-3 (2004)
M.W. Roomi, V. Ivanov, A. Niedzwiecki, M. Rath
Matthias Rath Research., Cancer Research Division, Santa Clara, CA 95050
Journal of Immunotherapy (Official journal of International Society for Biological Therapy of Cancer) volume 27, number 6, page S8, November/December 2004

.A Novel Approach to Inhibition of Cancer Development by Nutrient Supplement
M.W. Roomi, V. Ivanov, A. Niedzwiecki, M. Rath
Book of Abstracts, 229th ACS National Meeting, Abstract #86

Nutrition Synergy Inhibits MMP Expression and Invasion Potential of Human Lung Carcinoma Cell Line A-549 (2004)
M.W. Roomi, V. Ivanov, A. Niedzwiecki, M. Rath
Matthias Rath Research, Cancer Division, Santa Clara, CA 95050
ACN Symposium on Advances in Clinical Nutrition Program, Abstract #50, pg 465

.A Specific Combination of Ascorbic Acid, Lysine, Proline and Epigallocatechin Gallate Inhibits Proliferation and Extracellular Matrix Invasion of Various Human Cancer Cell Lines (2003)
Netke SP, Roomi MW, Roomi NW, Ivanov V, Niedzwiecki A, Rath M.
Research Communications in Pharmacology and Toxicology: Emerging Drugs, 2:37-5, 2003.

Anti-Tumorigenic Activity of Nutrient Synergy in Human Breast Cancer Lines MDA-MB-231 and MCF-7 (2003)
Roomi MW, Ivanov V, Niedzwiecki A, Rath M.

Inhibition of Tumor Growth of Human Breast, Prostate, Colon, and Melanoma Cancer Xenografts by Nutrient Synergy in Nude Mice (2003)
Roomi MW, Roomi NW, Ivanov V, Netke SP, Niedzwiecki A, Rath M.
Conference proceedings

A Specific Combination of Ascorbic Acid, Lysine, Proline and Epigallocatechin Gallate Inhibits Proliferation and Extracellular Matrix Invasion of Various Human Cancer Cell Lines (2003)
Netke SP, Roomi MW, Roomi NW, Ivanov V, Niedzwiecki A, Rath M.
Research Communications in Pharmacology and Toxicology: Emerging Drugs, 2:37-5, 2003.

Inhibition of Tumor Growth of Human Breast, Prostate, Colon and Melanoma Cancer Xenografts by Nutrient Synergy in Nude Mice (2003)
Roomi MW, Roomi NW, Ivanov V, Netke SP, Niedzwiecki A, Rath M.

Suppression of MMP Expression and Invasion of Human Cervical Cancer Cell lines Hela and DoTc2 4510 by Nutrients
M.W. Roomi, V. Ivanov, A. Niedzwiecki, M. Rath
Proceedings of the 44th Annual Meeting of the Society of Toxicology, Abstract #1494
Expression of matrix metalloproteinase 2 (MMP-2), memebrane-type 1 MMP and tissue inhibitor of matrix metalloproteinase 2 and activation of pro-MMP-2 in pancreatic duct adenocarcinomas in hamsters treated with N-nitorosobis(2-oxopropyl)amine
Katsumichi Iki, Madahiro tsutumi, Akira Kido, Hiroyuki Sakitani, Makoto Takahama, Masatoshi Yoshimoto, Masaaki Motoyama, Kunihiko Tasumi, Tsukasa Tunoda and Yoichi Konishi
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Ascorbic Acid Protects Guinea Pigs from Acute Aflatoxin Toxicity
P. Netke, W. Roomi, C. Tsao, A. Niedzwiecki
J. Toxicol. 143, 429-435. (1997)

Ascorbate Affects Proliferation of Guinea Pigs Vascular Smooth Muscle Cells by Direct and Extracellular Matrix Mediated Effects
V. O.Ivanov, S. Ivanova, A. Niedzwiecki
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Pharmacokinetics of tranexamic acid in patients with ulcerative colitis and in healthy volunteers after the single instillation of 2 g rectally.
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Vitamin C inhibits the growth of a bacterial risk factor for gastric carcinoma: Helicobacter pylori

Green Tea Compound EGCG May Turn Off Chain Reaction of Inflammation, Joint Damage in RA
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Specific nutrient combination effects on tax, NF-B and MMP-9 in human T-cell ymphotropic virus -1 positive malignant T-lymphocytes
Harakeh et al. BMC Cancer 2015, 15(Suppl 1):S2

Repression of matrix metalloproteinases and inhibition of cell invasion by a nutrient mixture, containing ascorbic acid, lysine, proline, and green tea extract on human fanconi anemia fibroblast cell lines
M.W. Roomi, N.W. Roomi, B. Bhanap, A. Niedzwiecki*, M. Rath Exp Oncol 2013 35, 1, 20–24

Lysine-specific demethylase 1-mediated demethylation of histone H3 lysine 9 contributes to interleukin 1β-induced microsomal prostaglandin E synthase 1 expression in human osteoarthritic chondrocytes
Arthritis Research & Therapy 2014, 16:R113
53.Analysis of the mechanism of inhibition of human matrix metalloproteinase 7 (MMP-7) activity by green tea catechins.
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Effect of L-lysine on nitric oxide overproduction in endotoxic shock.
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Green tea epigallocatechin gallate: a natural inhibitor of fatty-acid synthase.
Biochem. Biophys. Res. Commun. 288, 1200–1206 (2001)

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